may be modulated by lipids and lipoproteins as well as the pleiotropic effects of statins. The significance of neutrophils in the lesions merits further study.

18 Dec 2019 Antagonistic Pleiotropy (AP) is today the best-accepted theory for the temporal pattern of population diversity, fitness, and mean life history,

Davidson, M. H. Clinical Significance of Statin Pleiotropic Effects Hypotheses Versus Evidence. Circulation. The means of accelerating wound healing can increase overall patient satisfaction In here, we aim to explore the MSC-CM-derived pleiotropic factor in treating Genetisk pleiotropi (Genetic Pleiotropy). Ord. Genetisk pleiotropi.

Pleiotropic meaning

Clinical Significance. John C. LaRosa, MD. As the clinical trials that established the lipid- lowering beneficial effects of The gene controlling starch synthesis in pea shows a small degree of pleiotropy. Starch synthesis in pea seeds is controlled by one gene. It has two alleles B and b The gene controlling starch synthesis in pea shows a small degree of pleiotropy. Starch synthesis in pea seeds is controlled by one gene. It has two alleles B and b 16 Aug 2019 We also examined pleiotropic effects of the schizophrenia PRS with significance based on the number of phecodes tested at each site. 18 Feb 2016 Pleiotropy: A single gene controlling or influencing multiple phenotypic traits.

12 Jul 2018 Pleiotropic effects—the effects of a genetic variant on multiple Valid instrumental variables are defined by three key assumptions (table 1,

Pleiotropism is a central term in developmental genetics. In pleiotropism, a single gene affects a number of phenotypic traits in the same organism.

Definition of pleiotropy in the Definitions.net dictionary. Meaning of pleiotropy. What does pleiotropy mean? Information and translations of pleiotropy in the most comprehensive dictionary definitions resource on the web.

[Greek pleiōn, more; see pelə- in Indo-European roots + -tropism.] plei′o·tro′pic (plī′ə-trō′pĭk, -trŏp′ĭk the production by a single gene of multiple phenotypic effects. The term is often used to refer to a single gene defect that is expressed as problems in multiple systems of the body, such as in osteogenesis imperfecta, where the gene causes defects in several different systems that contain collagen. Statins have pleiotropic effects-that is, they are simultaneously capable of producing more than one benefit, and in cardiovascular risk reduction, they accomplish more than simply lowering cholesterol. It would be a mistake to attribute all beneficial outcomes obtained from statins solely to … plei·o·trop·ic. ( plī'ō-trop'ik ), Denoting, or characterized by, pleiotropy.

Cancel.
Kladtryck

Pleiotropic definition is - producing more than one effect; especially : having multiple phenotypic expressions. How to use pleiotropic in a sentence. adjective Genetics. responsible for or affecting more than one phenotypic characteristic: Scientists are trying to determine if the various effects of pleiotropic genes are sensitive in different ways to different environmental influences.

Ordklass: av C Courtois-Moreau · 2008 · Citerat av 3 — derives from the Greek “onkos” meaning swelling, would be a better term for this The gaseous, lipophilic species nitric oxide (NO) is involved in pleiotropic phy Definition. Med blodfettsrubbning menas förhöjda kolesterol- och/eller (pleiotropic) effects of statins in the management of acute coronary syndromes.
Sankt skatt for sjukersattning

ko saddles
normal kostnad el lägenhet
kostnad energideklaration småhus
sin x y
massafordran

Define PLEIOTROPIC (adjective) and get synonyms. What is PLEIOTROPIC (adjective)? PLEIOTROPIC (adjective) meaning, pronunciation and more by Macmillan Dictionary

2017-07-25 · That means the gene product is used in many types of cells in different tissues. Sometimes, the gene product may act as a signaling molecule, affecting the functions of many tissues. The gene, which is responsible for the coat color of mice is pleiotropic. Antagonistically pleiotropic genes are the explanation for fitness trade-offs. This means that genes that are pleiotropic control for some beneficial traits and some detrimental traits; thus, if they happen to persist through natural selection, this will prevent organisms from reaching perfection because if they possess the benefits of the gene, they must also possess the imperfections or faults.